STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHD1EH domain containing 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (563 aa)    
Predicted Functional Partners:
MICALL1
MICAL like 1.
    
 
 0.975
RBSN
Rabenosyn, RAB effector.
    
 0.958
RAB11FIP2
RAB11 family interacting protein 2.
    
 0.941
RAB11FIP1
RAB11 family interacting protein 1.
    
 0.923
RAB11FIP5
RAB11 family interacting protein 5.
     
 0.914
VPS45
Vacuolar protein sorting 45 homolog; Belongs to the STXBP/unc-18/SEC1 family.
    
 0.730
EEA1
Early endosome antigen 1.
    
 
 0.681
MICAL1
Microtubule associated monooxygenase, calponin and LIM domain containing 1.
   
 
 0.592
RAB5A
Ras-related protein Rab-5A; Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Active GTP-bound form is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulati [...]
     
 0.567
LSM14A
LSM14A mRNA processing body assembly factor.
      
 0.562
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.