STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BTG4BTG anti-proliferation factor 4. (224 aa)    
Predicted Functional Partners:
NLRP5
NLR family pyrin domain containing 5.
   
  
 0.678
CNOT7
CCR4-NOT transcription complex subunit 7.
    
 
 0.656
RNF34
Ring finger protein 34.
      
 0.635
CNOT8
CCR4-NOT transcription complex subunit 8.
    
 
 0.566
CPEB1
RRM domain-containing protein.
   
 
 0.565
WEE2
Wee1-like protein kinase 2; Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1 and acts as a key regulator of meiosis during both prophase I and metaphase II. Required to maintain meiotic arrest in oocytes during the germinal vesicle (GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry. Also required for metaphase II exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and promote pronuclear formation ( [...]
   
  
 0.562
RASL11A
RAS like family 11 member A.
      
 0.562
CNOT6L
CCR4-NOT transcription complex subunit 6 like.
    
 
 0.554
CNBP
CCHC-type zinc finger nucleic acid binding protein.
      
 0.533
ARMC1
Armadillo repeat-containing protein 1.
   
  
 0.527
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.