STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EXPH5Exophilin 5. (1998 aa)    
Predicted Functional Partners:
TGM5
Transglutaminase 5.
   
  
 0.793
KLHL24
Kelch like family member 24.
      
 0.789
RPH3A
Rabphilin 3A.
   
  
 0.784
PKP1
Uncharacterized protein.
   
  
 0.753
FERMT1
Fermitin family member 1.
   
  
 0.648
LOC100855871
Uncharacterized protein.
      
 0.573
PLEC
Plectin.
      
 0.572
RAB27A
Ras-related protein Rab-27A; Small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate homeostasis of late endocytic pathway, including endosomal positioning, maturation and secretion. Plays a role in cytotoxic granule exocytosis in lymphocytes. Required for both granule maturation and granule docking and priming at the immunologic synapse.
    
 
 0.567
LETM2
Leucine zipper and EF-hand containing transmembrane protein 2.
      
 0.564
ALPK2
Alpha kinase 2.
  
     0.512
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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