STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RABGAP1LRAB GTPase activating protein 1 like. (815 aa)    
Predicted Functional Partners:
RAB34
RAB34, member RAS oncogene family.
   
 
 0.752
RAB22A
Ras-related protein Rab-22A; Plays a role in endocytosis and intracellular protein transport. Mediates trafficking of TF from early endosomes to recycling endosomes. Required for NGF-mediated endocytosis of NTRK1, and subsequent neurite outgrowth (By similarity). Binds GTP and GDP and has low GTPase activity. Alternates between a GTP-bound active form and a GDP-bound inactive form.
    
 
 0.598
TRIB1
Protein kinase domain-containing protein.
    
 
 0.560
GRID2
Glutamate ionotropic receptor delta type subunit 2.
      
 0.550
IQGAP3
IQ motif containing GTPase activating protein 3.
      
 0.526
TBCC
Tubulin folding cofactor C.
      
 0.525
ACAP1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1.
    
 
 0.515
ALS2CL
ALS2 C-terminal like.
      
 0.508
ARHGAP1
Cdc42 GTPase-activating protein.
   
  
 0.491
MTHFS
5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
      
 0.483
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.