STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KCNK4Potassium two pore domain channel subfamily K member 4; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (394 aa)    
Predicted Functional Partners:
GPR137
G protein-coupled receptor 137.
 
    
 0.894
MEX3C
Mex-3 RNA binding family member C.
      
 0.873
KCNK12
Potassium two pore domain channel subfamily K member 12; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
   
 
0.838
CCDC88B
Non-specific serine/threonine protein kinase.
      
 0.819
TRMT112
tRNA methyltransferase subunit 11-2.
      
 0.813
SGSM2
Small G protein signaling modulator 2.
      
 0.738
KCNK18
Potassium two pore domain channel subfamily K member 18; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
   
 
0.717
KCNK13
Potassium two pore domain channel subfamily K member 13; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
   
 
0.652
SPTSSB
Serine palmitoyltransferase small subunit B.
      
 0.627
KCNK15
Potassium two pore domain channel subfamily K member 15; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
   
 
0.625
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.