STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZBTB37Zinc finger and BTB domain containing 37. (503 aa)    
Predicted Functional Partners:
SMG7
SMG7 nonsense mediated mRNA decay factor.
    
 
 0.806
MPHOSPH6
M-phase phosphoprotein 6.
      
 0.797
NPL
N-acetylneuraminate pyruvate lyase; Belongs to the DapA family.
   
 
 0.784
TMEM132C
Transmembrane protein 132C.
      
 0.759
AACS
Transmembrane protein 132B.
      
 0.755
FER
Tyrosine-protein kinase Fer; Tyrosine-protein kinase that acts downstream of cell surface receptors for growth factors and plays a role in the regulation of the actin cytoskeleton, microtubule assembly, lamellipodia formation, cell attachment and cell migration. Acts downstream of EGFR, PDGFRA and PDGFRB. Acts downstream of EGFR to promote activation of NF-kappa-B and cell proliferation. Acts downstream of the activated FCER1 receptor and plays a role in FCER1 (high affinity immunoglobulin epsilon receptor)- mediated signaling in mast cells. Plays a role in the regulation of mast cell [...]
    
 
 0.714
CMIP
C-Maf inducing protein.
      
 0.690
KIAA0040
KIAA0040.
      
 0.668
SLC9C2
Solute carrier family 9 member C2 (putative).
    
 
 0.662
TEX50
Testis expressed 50.
      
 0.660
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.