STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TNFSF4Tumor necrosis factor ligand 2B; Belongs to the tumor necrosis factor family. (183 aa)    
Predicted Functional Partners:
TNFRSF4
TNF receptor superfamily member 4.
   
 0.996
P2RY11
G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.
      
 0.788
CTSH
Cathepsin H; Belongs to the peptidase C1 family.
   
  
 0.685
SSPO
SCO-spondin.
   
  
 0.647
FAM167A
Family with sequence similarity 167 member A.
      
 0.645
TNFRSF9
TNF receptor superfamily member 9.
   
  
 0.618
TNFSF18
TNF superfamily member 18.
      
 0.607
BANK1
B cell scaffold protein with ankyrin repeats 1.
      
 0.570
PBX2
PBX homeobox 2.
   
  
 0.566
TNFSF9
TNF superfamily member 9; Belongs to the tumor necrosis factor family.
   
  
 0.565
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.