HTT protein (Canis lupus familiaris) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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[Homology]

Score

HTT

Huntingtin. (3130 aa)

Predicted Functional Partners:

HIP1

0.984

ITPR1

0.978

TAF4

0.970

AP2A2

0.965

HIP1R

0.961

UQCRC1

0.951

UQCRC2

0.951

PSMC2

0.949

CREBBP

0.949

BECN1

0.937

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AP2A2	HIP1	ENSCAFP00000044197	ENSCAFP00000019716	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	Huntingtin interacting protein 1.	0.899
AP2A2	HIP1R	ENSCAFP00000044197	ENSCAFP00000011536	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	Huntingtin interacting protein 1 related.	0.732
AP2A2	HTT	ENSCAFP00000044197	ENSCAFP00000021648	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	Huntingtin.	0.965
BECN1	HTT	ENSCAFP00000047143	ENSCAFP00000021648	Beclin 1.	Huntingtin.	0.937
BECN1	ITPR1	ENSCAFP00000047143	ENSCAFP00000008870	Beclin 1.	Inositol 1,4,5-trisphosphate receptor type 1.	0.899
CREBBP	HTT	ENSCAFP00000036447	ENSCAFP00000021648	CREB binding protein.	Huntingtin.	0.949
HIP1	AP2A2	ENSCAFP00000019716	ENSCAFP00000044197	Huntingtin interacting protein 1.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.899
HIP1	HIP1R	ENSCAFP00000019716	ENSCAFP00000011536	Huntingtin interacting protein 1.	Huntingtin interacting protein 1 related.	0.938
HIP1	HTT	ENSCAFP00000019716	ENSCAFP00000021648	Huntingtin interacting protein 1.	Huntingtin.	0.984
HIP1R	AP2A2	ENSCAFP00000011536	ENSCAFP00000044197	Huntingtin interacting protein 1 related.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.732
HIP1R	HIP1	ENSCAFP00000011536	ENSCAFP00000019716	Huntingtin interacting protein 1 related.	Huntingtin interacting protein 1.	0.938
HIP1R	HTT	ENSCAFP00000011536	ENSCAFP00000021648	Huntingtin interacting protein 1 related.	Huntingtin.	0.961
HTT	AP2A2	ENSCAFP00000021648	ENSCAFP00000044197	Huntingtin.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.965
HTT	BECN1	ENSCAFP00000021648	ENSCAFP00000047143	Huntingtin.	Beclin 1.	0.937
HTT	CREBBP	ENSCAFP00000021648	ENSCAFP00000036447	Huntingtin.	CREB binding protein.	0.949
HTT	HIP1	ENSCAFP00000021648	ENSCAFP00000019716	Huntingtin.	Huntingtin interacting protein 1.	0.984
HTT	HIP1R	ENSCAFP00000021648	ENSCAFP00000011536	Huntingtin.	Huntingtin interacting protein 1 related.	0.961
HTT	ITPR1	ENSCAFP00000021648	ENSCAFP00000008870	Huntingtin.	Inositol 1,4,5-trisphosphate receptor type 1.	0.978
HTT	PSMC2	ENSCAFP00000021648	ENSCAFP00000006249	Huntingtin.	Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family.	0.949
HTT	TAF4	ENSCAFP00000021648	ENSCAFP00000018423	Huntingtin.	TATA-box binding protein associated factor 4.	0.970