STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FBN1Uncharacterized protein. (2871 aa)    
Predicted Functional Partners:
LUM
Lumican.
   
 
 0.997
ELN
Elastin.
   
 
 0.943
DCN
Decorin; May affect the rate of fibrils formation; Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
   
 
 0.925
COL5A2
Collagen type V alpha 2 chain.
   
 
 0.912
ADAMTS10
ADAM metallopeptidase with thrombospondin type 1 motif 10.
    
 
 0.892
ADAMTSL4
ADAMTS like 4.
    
 
 0.885
COL1A2
Collagen alpha-2(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Belongs to the fibrillar collagen family.
   
 
 0.883
MFAP2
Microfibril associated protein 2.
   
 0.865
MFAP5
Microfibril associated protein 5.
   
 0.852
COL3A1
Collagen type III alpha 1 chain.
   
 
 0.843
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.