STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
COPS6COP9 signalosome subunit 6. (321 aa)    
Predicted Functional Partners:
COPS5
COP9 signalosome subunit 5.
   
 0.997
COPS4
COP9 signalosome subunit 4.
   
 0.997
COPS3
COP9 signalosome subunit 3.
   
 0.995
COPS2
COP9 signalosome subunit 2.
   
 0.995
GPS1
G protein pathway suppressor 1.
   
 0.994
COPS8
PCI domain-containing protein.
   
 0.983
COPS7A
COP9 signalosome subunit 7A.
   
 0.981
COPS7B
COP9 signalosome subunit 7B.
   
 0.976
NEDD8
NEDD8 ubiquitin like modifier.
   
 0.967
J9NSW9_CANLF
CSN8_PSD8_EIF3K domain-containing protein.
   
 
 0.917
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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