STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDK5R2Cyclin-dependent kinase 5 activator. (370 aa)    
Predicted Functional Partners:
ENSCAFP00000053140
Uncharacterized protein.
    
 
 0.725
CDK5
Cyclin dependent kinase 5.
    
 
 0.725
CRYBA2
Crystallin beta A2; Belongs to the beta/gamma-crystallin family.
      
 0.515
DNAJC5B
DnaJ heat shock protein family (Hsp40) member C5 beta.
   
  
 0.507
LRCH1
Leucine rich repeats and calponin homology domain containing 1.
      
 0.479
NEURL4
Uncharacterized protein.
      
 0.463
LOC610380
Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.
   
  
 0.459
MAPT
Microtubule-associated protein.
   
 
 0.452
CDK14
Cyclin dependent kinase 14; Belongs to the protein kinase superfamily.
    
 
 0.426
DNM1
Dynamin 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
   
  
 0.402
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.