Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
TMEM129Transmembrane protein 129. (362 aa)    
Predicted Functional Partners:
DERL1
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
    
 
 0.856
FAM53A
Family with sequence similarity 53 member A.
      
 0.837
ENKD1
Enkurin domain containing 1.
      
 0.811
SLBP
Stem-loop binding protein.
 
    
 0.769
UBE2J2
Ubiquitin conjugating enzyme E2 J2.
    
 
 0.702
CLHC1
Clathrin heavy chain linker domain containing 1.
      
 0.694
CCDC102A
Coiled-coil domain containing 102A.
      
 0.692
DENND4B
DENN domain containing 4B.
      
 0.692
SCRN1
Secernin 1.
      
 0.687
TACC3
Transforming acidic coiled-coil containing protein 3.
      
 0.627
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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