STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CDACytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (146 aa)    
Predicted Functional Partners:
UPP1-2
PNP_UDP_1 domain-containing protein.
  
 
 0.994
DCK
Deoxycytidine kinase.
  
 
 0.991
TK1
Thymidine kinase.
  
 
 0.988
UCK2
Uridine-cytidine kinase 2.
  
 
 0.987
PNP
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
 0.936
UPP1
PNP_UDP_1 domain-containing protein.
  
 
 0.936
NT5E
5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family.
    
 0.927
NT5C3B
5'-nucleotidase; Belongs to the pyrimidine 5'-nucleotidase family.
     
 0.927
CES2
Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
     
 0.925
NT5C2
5'-nucleotidase, cytosolic II.
   
 
 0.916
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.