STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MUL1Mitochondrial E3 ubiquitin protein ligase 1. (483 aa)    
Predicted Functional Partners:
HP1BP3
Heterochromatin protein 1 binding protein 3.
      
 0.872
MPV17L2
MPV17 mitochondrial inner membrane protein like 2; Belongs to the peroxisomal membrane protein PXMP2/4 family.
   
  
 0.685
TRIM56
Tripartite motif containing 56.
   
  
 0.681
MAP3K6
Mitogen-activated protein kinase kinase kinase 6.
      
 0.680
MFN2
Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
   
 
 0.675
AMFR
Autocrine motility factor receptor.
      
 0.671
USP30
Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family.
     
 0.669
TMEM115
Transmembrane protein 115.
   
    0.666
TOMM70
Translocase of outer mitochondrial membrane 70.
     
 0.584
SLC25A51
Uncharacterized protein; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.560
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.