STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MMP27Matrix metallopeptidase 27. (512 aa)    
Predicted Functional Partners:
TIMP2
Metalloproteinase inhibitor 2; Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor; Belongs to the protease inhibitor I35 (TIMP) family.
   
 
 0.641
KANK3
KN motif and ankyrin repeat domains 3.
      
 0.607
KIAA1755
KIAA1755.
    
 
 0.575
PLXDC1
Plexin domain containing 1.
   
  
 0.571
SLC35F1
Solute carrier family 35 member F1.
   
  
 0.517
FGL1
Fibrinogen like 1.
   
 
 0.516
PTPRU
Protein tyrosine phosphatase receptor type U.
   
 
 0.512
TIMP3
TIMP metallopeptidase inhibitor 3.
   
 
 0.510
KIF26A
Kinesin family member 26A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
      
 0.506
TIMP4
Metalloproteinase inhibitor 4.
    
 
 0.493
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (20%) [HD]