STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RNF186Ring finger protein 186. (232 aa)    
Predicted Functional Partners:
SVOPL
SVOP like.
      
 0.676
OTUD3
OTU deubiquitinase 3.
    
 
 0.675
PLA2G2E
Phospholipase A(2).
   
  
 0.672
CARD9
Caspase recruitment domain family member 9.
   
 
 0.592
BTNL2
Butyrophilin like 2.
    
 
 0.569
PUS10
Pseudouridine synthase 10.
      
 0.563
UBE2H
Ubiquitin conjugating enzyme E2 H; Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.549
PSMG1
Proteasome assembly chaperone 1; Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with psmg2.
   
  
 0.525
GSDMC
Gasdermin C.
   
  
 0.516
CEP72
Centrosomal protein 72.
      
 0.515
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.