STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F5Coagulation factor V; Belongs to the multicopper oxidase family. (2222 aa)    
Predicted Functional Partners:
F2
Coagulation factor II, thrombin; Belongs to the peptidase S1 family.
    
 0.975
F7
Coagulation factor X.
   
 0.974
PROS1
Protein S.
   
 0.890
PROC
Vitamin K-dependent protein C heavy chain; Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids. Exerts a protective effect on the endothelial cell barrier function. Belongs to the peptidase S1 family.
    
 0.845
SERPINE2
Serpin family E member 2; Belongs to the serpin family.
   
 0.767
F13B
Coagulation factor XIII B chain.
   
 0.741
LMAN1
Lectin, mannose binding 1.
    
 0.736
MASP2
Mannan binding lectin serine peptidase 2; Belongs to the peptidase S1 family.
    
 
 0.734
MCFD2
Multiple coagulation factor deficiency 2.
     
 0.707
MASP1
Mannan binding lectin serine peptidase 1; Belongs to the peptidase S1 family.
    
 
 0.672
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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