STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AP5M1Adaptor related protein complex 5 subunit mu 1; Belongs to the adaptor complexes medium subunit family. (496 aa)    
Predicted Functional Partners:
GOLIM4
Golgi integral membrane protein 4.
      
 0.826
AP4E1
Adaptor related protein complex 4 subunit epsilon 1.
   
 
 0.822
SUSD1
Sushi domain containing 1.
    
 
 0.793
AP4B1
AP complex subunit beta; Belongs to the adaptor complexes large subunit family.
   
 
 0.792
AP5Z1
Adaptor related protein complex 5 subunit zeta 1.
      
 0.792
TBC1D9B
TBC1 domain family member 9B.
      
 0.769
AP4S1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
    
 
 0.768
SPG11
SPG11 vesicle trafficking associated, spatacsin.
    
 
 0.761
AP2B1
AP complex subunit beta.
   
 
 0.742
AP1B1
AP complex subunit beta.
   
 
 0.731
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.