NME7 protein (Canis lupus familiaris) - STRING interaction network

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Score

NME7

Nucleoside diphosphate kinase 7; Belongs to the NDK family. (376 aa)

Predicted Functional Partners:

HDDC3

0.949

RRM1

0.948

NTPCR

0.947

CMPK1

0.944

AK9

0.940

CTPS1

0.938

CTPS2

0.938

MZT1

0.935

RRM2B

0.928

RRM2

0.928

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AK9	CMPK1	ENSCAFP00000005720	ENSCAFP00000047166	Adenylate kinase 9.	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	0.920
AK9	CTPS1	ENSCAFP00000005720	ENSCAFP00000004062	Adenylate kinase 9.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	0.939
AK9	CTPS2	ENSCAFP00000005720	ENSCAFP00000049397	Adenylate kinase 9.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	0.939
AK9	HDDC3	ENSCAFP00000005720	ENSCAFP00000018036	Adenylate kinase 9.	HD domain containing 3.	0.939
AK9	NME7	ENSCAFP00000005720	ENSCAFP00000022471	Adenylate kinase 9.	Nucleoside diphosphate kinase 7; Belongs to the NDK family.	0.940
AK9	NTPCR	ENSCAFP00000005720	ENSCAFP00000017063	Adenylate kinase 9.	Uncharacterized protein.	0.911
AK9	RRM1	ENSCAFP00000005720	ENSCAFP00000008963	Adenylate kinase 9.	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.980
AK9	RRM2	ENSCAFP00000005720	ENSCAFP00000062946	Adenylate kinase 9.	Ribonucleotide reductase regulatory subunit M2.	0.977
AK9	RRM2B	ENSCAFP00000005720	ENSCAFP00000000854	Adenylate kinase 9.	Ribonucleotide reductase regulatory TP53 inducible subunit M2B.	0.977
CMPK1	AK9	ENSCAFP00000047166	ENSCAFP00000005720	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Adenylate kinase 9.	0.920
CMPK1	CTPS1	ENSCAFP00000047166	ENSCAFP00000004062	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	0.407
CMPK1	CTPS2	ENSCAFP00000047166	ENSCAFP00000049397	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	0.407
CMPK1	HDDC3	ENSCAFP00000047166	ENSCAFP00000018036	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	HD domain containing 3.	0.419
CMPK1	NME7	ENSCAFP00000047166	ENSCAFP00000022471	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Nucleoside diphosphate kinase 7; Belongs to the NDK family.	0.944
CMPK1	RRM1	ENSCAFP00000047166	ENSCAFP00000008963	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.952
CMPK1	RRM2	ENSCAFP00000047166	ENSCAFP00000062946	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Ribonucleotide reductase regulatory subunit M2.	0.938
CMPK1	RRM2B	ENSCAFP00000047166	ENSCAFP00000000854	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Ribonucleotide reductase regulatory TP53 inducible subunit M2B.	0.930
CTPS1	AK9	ENSCAFP00000004062	ENSCAFP00000005720	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	Adenylate kinase 9.	0.939
CTPS1	CMPK1	ENSCAFP00000004062	ENSCAFP00000047166	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	0.407
CTPS1	CTPS2	ENSCAFP00000004062	ENSCAFP00000049397	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.	0.956