STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FBXL5F-box and leucine rich repeat protein 5. (691 aa)    
Predicted Functional Partners:
IREB2
Iron responsive element binding protein 2; Belongs to the aconitase/IPM isomerase family.
    
 0.983
SKP1
S-phase kinase associated protein 1; Belongs to the SKP1 family.
   
 0.966
CUL1
Cullin 1; Belongs to the cullin family.
   
 0.957
HAUS3
HAUS augmin like complex subunit 3.
      
 0.804
NSUN7
NOP2/Sun RNA methyltransferase family member 7; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
      
 0.777
ENSCAFP00000049197
Uncharacterized protein; Belongs to the SKP1 family.
    
 
 0.766
ENSCAFP00000051783
Uncharacterized protein; Belongs to the SKP1 family.
    
 
 0.766
ENSCAFP00000063226
Uncharacterized protein; Belongs to the SKP1 family.
    
 
 0.766
ACO1
Aconitase 1; Belongs to the aconitase/IPM isomerase family.
   
 
 0.756
CSKMT
Citrate synthase lysine methyltransferase.
      
 0.732
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.