STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM221Uncharacterized protein. (291 aa)    
Predicted Functional Partners:
GPR137C
G protein-coupled receptor 137C.
      
 0.769
TMEM171
Transmembrane protein 171.
      
 0.769
TMEM132E
Transmembrane protein 132E.
      
 0.714
TMEM38A
Transmembrane protein 38A.
   
  
 0.684
TMEM45A
Transmembrane protein 45A.
      
 0.679
OPRD1
Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family.
      
 0.651
GPR37
G protein-coupled receptor 37.
      
 0.609
TMEM211
Transmembrane protein 211.
      
 0.559
GPR153
Protein-S-isoprenylcysteine O-methyltransferase.
      
 0.524
GPR162
G protein-coupled receptor 162.
      
 0.524
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.