STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DACT1Dishevelled binding antagonist of beta catenin 1. (860 aa)    
Predicted Functional Partners:
DVL2
Dishevelled segment polarity protein 2.
    
 0.973
VANGL1
Vang-like protein.
    
 
 0.733
SESTD1
SEC14 and spectrin domain containing 1.
   
 
 0.683
LOC489647
Uncharacterized protein.
      
 0.671
PRICKLE1
Prickle planar cell polarity protein 1.
      
 0.670
SCRIB
Scribble planar cell polarity protein.
      
 0.649
CELSR1
Cadherin EGF LAG seven-pass G-type receptor 1; Belongs to the G-protein coupled receptor 2 family.
      
 0.646
LRRC17
Leucine rich repeat containing 17.
      
 0.645
DVL3
Dishevelled segment polarity protein 3.
    
 
 0.609
DVL1
Dishevelled segment polarity protein 1.
    
 
 0.597
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.