STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GATA1GATA binding protein 1. (412 aa)    
Predicted Functional Partners:
LMO2
LIM domain only 2.
    
 
 0.985
TAL1
TAL bHLH transcription factor 1, erythroid differentiation factor.
   
 
 0.972
LDB1
LIM domain binding 1.
   
 
 0.886
KLF1
Kruppel like factor 1.
   
 
 0.843
EP300
E1A binding protein p300.
    
 0.731
GFI1B
Growth factor independent 1B transcriptional repressor.
   
 
 0.731
BRD3
Bromodomain containing 3.
   
 
 0.715
ZFPM2
Zinc finger protein, FOG family member 2.
    
 0.683
ALAS2
5-aminolevulinate synthase.
   
 
 0.647
NKX2-5
Transcription factor NKX2.5.
   
 
 0.646
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.