STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DHRS7Dehydrogenase/reductase 7; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (349 aa)    
Predicted Functional Partners:
TMEM126A
Transmembrane protein 126A.
   
  
 0.827
TMEM38A
Transmembrane protein 38A.
   
  
 0.734
SUN3
Sad1 and UNC84 domain containing 3.
    
 
 0.662
KIAA2013
KIAA2013.
   
  
 0.592
HAO2
Hydroxyacid oxidase 2.
   
 0.587
HECTD3
HECT domain E3 ubiquitin protein ligase 3.
   
 
 0.575
TMUB1
Transmembrane and ubiquitin like domain containing 1.
    
 
 0.570
ALDH8A1
Aldehyde dehydrogenase 8 family member A1; Belongs to the aldehyde dehydrogenase family.
   
 0.545
NUP133
Nucleoporin 133.
    
 
 0.524
GSS
Glutathione synthetase.
   
  
 0.518
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.