STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIX6SIX homeobox 6. (246 aa)    
Predicted Functional Partners:
LRRC9
Leucine rich repeat containing 9.
   
 
 0.807
OTX2
Orthodenticle homeobox 2.
   
 
 0.723
VSX2
Visual system homeobox 2.
   
  
 0.646
GBX2
Gastrulation brain homeobox 2.
   
  
 0.607
ZNRD2
Zinc ribbon domain containing 2.
   
  
 0.578
LHX2
LIM homeobox 2.
   
 
 0.570
HESX1
HESX homeobox 1.
   
 
 0.536
KCNG4
Potassium voltage-gated channel modifier subfamily G member 4; Belongs to the potassium channel family.
   
  
 0.517
LOC111089966
Uncharacterized protein.
   
 
 0.514
EYA1
Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family.
   
 
 0.497
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.