STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RHNO1RAD9-HUS1-RAD1 interacting nuclear orphan 1. (255 aa)    
Predicted Functional Partners:
RAD1
RAD1 checkpoint DNA exonuclease.
    
 0.941
TOPBP1
DNA topoisomerase II binding protein 1.
    
 0.908
HUS1
HUS1 checkpoint clamp component.
    
 0.875
CLSPN
Claspin.
     
 0.872
RAD9A
Cell cycle checkpoint control protein; Belongs to the rad9 family.
    
 0.867
CHEK1
Checkpoint kinase 1.
   
 
 0.822
BRIP1
BRCA1 interacting protein C-terminal helicase 1.
     
  0.800
PWP1
PWP1 homolog, endonuclein.
      
 0.783
RAD9B
Cell cycle checkpoint control protein; Belongs to the rad9 family.
    
 0.779
DCAF11
DDB1- and CUL4-associated factor 11; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; Belongs to the WD repeat LEC14B family.
      
 0.744
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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