STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NRIP2Nuclear receptor interacting protein 2. (240 aa)    
Predicted Functional Partners:
RAD23B
RAD23 homolog B, nucleotide excision repair protein.
   
 
 0.645
RAD23A
RAD23 homolog A, nucleotide excision repair protein.
   
 
 0.645
RPS27A
Ubiquitin-like domain-containing protein.
   
 
 0.606
ENSCAFP00000050780
Ubiquitin-like domain-containing protein.
   
 
 0.606
MROH1
Maestro heat like repeat family member 1.
      
 0.605
C24H20orf194
Chromosome 24 C20orf194 homolog.
   
  
 0.564
TLCD4
TLCD4-RWDD3 readthrough.
      
 0.563
PSMD2
26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.
    
 
 0.531
PSTPIP2
Proline-serine-threonine phosphatase interacting protein 2.
   
  
 0.515
AAGAB
Alpha and gamma adaptin binding protein.
      
 0.515
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.