STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DNAJC7DnaJ heat shock protein family (Hsp40) member C7. (494 aa)    
Predicted Functional Partners:
BAG5
BCL2 associated athanogene 5.
   
 
 0.799
HSPA4
Heat shock 70 kDa protein 4.
   
 0.766
PSMD14
Proteasome 26S subunit, non-ATPase 14.
   
 
 0.713
SUGT1
SGT1 homolog, MIS12 kinetochore complex assembly cochaperone.
   
 
 0.679
MAGED2
MAGE family member D2.
   
  
 0.679
STUB1
STIP1 homology and U-box containing protein 1.
   
 
 0.670
HSP90B1
Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins (By similarity). When associated with CNPY3, required for proper folding of Toll-like receptors (By similarity). Functions in endoplasmic reticulum associated degradation (ERAD) (By similarity). Has ATPase activity. Belongs to the heat shock protein 90 family.
   
 
 0.664
QARS1
Glutaminyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
   
  
 0.650
RNF40
E3 ubiquitin protein ligase; Belongs to the BRE1 family.
   
 
 0.650
PSMC5
Proteasome 26S subunit, ATPase 5; Belongs to the AAA ATPase family.
   
 
 0.646
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.