STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RCC2Regulator of chromosome condensation 2. (501 aa)    
Predicted Functional Partners:
PLK1
Serine/threonine-protein kinase PLK.
   
 0.862
CDC20
Cell division cycle 20.
   
 0.858
NUDC
Nuclear distribution C, dynein complex regulator.
   
  0.825
MIS18A
MIS18 kinetochore protein A.
   
  
 0.706
CORO1C
Coronin; Belongs to the WD repeat coronin family.
   
 
 0.597
MAD2L1
HORMA domain-containing protein.
   
 
 0.571
BUB1B
BUB1 mitotic checkpoint serine/threonine kinase B.
   
 
 0.567
NCAPD3
Condensin-2 complex subunit D3; Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis.
   
 
 0.564
DCLRE1A
DNA cross-link repair 1A.
   
  
 0.564
CSNK2A1
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 
 0.533
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.