STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VMO1Vitelline membrane outer layer 1 homolog. (201 aa)    
Predicted Functional Partners:
CHID1
Chitinase domain containing 1; Belongs to the glycosyl hydrolase 18 family.
    
 
 0.760
TRAPPC1
Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family.
      
 0.675
LOC487083
Uncharacterized protein; Belongs to the glycosyl hydrolase 22 family.
      
 0.673
BORCS6
BLOC-1 related complex subunit 6.
      
 0.664
ACSF2
Acyl-CoA synthetase family member 2.
   
 
 0.652
KIF21A
Kinesin family member 21A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
      
 0.651
TIMM21
Translocase of inner mitochondrial membrane 21.
      
 0.640
GUCY1A2
Guanylate cyclase 1 soluble subunit alpha 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
   
 
 0.634
WSCD1
WSC domain containing 1.
    
 
 0.633
EPB41
Protein 4.1; Protein 4.1 is a major structural element of the erythrocyte membrane skeleton. It plays a key role in regulating membrane physical properties of mechanical stability and deformability by stabilizing spectrin-actin interaction. Recruits DLG1 to membranes. Required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase.
   
 
 0.617
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.