STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF19Rho guanine nucleotide exchange factor 19. (704 aa)    
Predicted Functional Partners:
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor 6.
      
 0.773
ARHGEF9
Cdc42 guanine nucleotide exchange factor 9.
      
 0.679
ARHGEF38
Rho guanine nucleotide exchange factor 38.
      
 0.677
SPSB4
SplA/ryanodine receptor domain and SOCS box containing 4.
   
  
 0.668
KIAA1109
KIAA1109.
      
 0.667
STK17A
Serine/threonine kinase 17a.
      
 0.651
ALS2CL
ALS2 C-terminal like.
   
  
 0.649
NOSIP
Nitric oxide synthase interacting protein.
      
 0.631
ECT2L
Epithelial cell transforming 2 like.
      
 0.626
PPP1R1A
Protein phosphatase 1 regulatory inhibitor subunit 1A.
      
 0.600
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.