STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RNF216Ring finger protein 216. (927 aa)    
Predicted Functional Partners:
KIF26B
Kinesin family member 26B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
      
 0.870
ZBTB18
Zinc finger and BTB domain containing 18.
    
 
 0.792
OTUD4
OTU deubiquitinase 4.
   
 
 0.771
RASSF2
Ras association domain family member 2.
   
  
 0.734
SACS
Sacsin molecular chaperone.
   
 
 0.702
RNF14
RBR-type E3 ubiquitin transferase.
   
  
 0.701
ZNF280D
Zinc finger protein 280D.
   
 
 0.694
WDR70
WD repeat domain 70.
   
  
 0.680
BCL2L13
BCL2 like 13.
      
 0.673
TIAM2
T cell lymphoma invasion and metastasis 2.
      
 0.670
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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