node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C5H16orf74 | TNS4 | ENSCAFP00000055685 | ENSCAFP00000023638 | Chromosome 5 C16orf74 homolog. | Tensin 4. | 0.526 |
CDKN2D | TNS4 | ENSCAFP00000048583 | ENSCAFP00000023638 | Cyclin dependent kinase inhibitor 2D. | Tensin 4. | 0.498 |
EXOC6B | TNS1 | ENSCAFP00000013203 | ENSCAFP00000061457 | Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. | Tensin 1. | 0.536 |
EXOC6B | TNS4 | ENSCAFP00000013203 | ENSCAFP00000023638 | Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. | Tensin 4. | 0.537 |
HGF | ITGB1 | ENSCAFP00000009539 | ENSCAFP00000005722 | Hepatocyte growth factor alpha chain; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization (By similarity); Belongs to the peptidase S1 family. Plasminogen subfamily. | Integrin beta; Belongs to the integrin beta chain family. | 0.740 |
HGF | MET | ENSCAFP00000009539 | ENSCAFP00000041478 | Hepatocyte growth factor alpha chain; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization (By similarity); Belongs to the peptidase S1 family. Plasminogen subfamily. | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | 0.998 |
HGF | TNS4 | ENSCAFP00000009539 | ENSCAFP00000023638 | Hepatocyte growth factor alpha chain; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization (By similarity); Belongs to the peptidase S1 family. Plasminogen subfamily. | Tensin 4. | 0.501 |
ITGB1 | HGF | ENSCAFP00000005722 | ENSCAFP00000009539 | Integrin beta; Belongs to the integrin beta chain family. | Hepatocyte growth factor alpha chain; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization (By similarity); Belongs to the peptidase S1 family. Plasminogen subfamily. | 0.740 |
ITGB1 | MET | ENSCAFP00000005722 | ENSCAFP00000041478 | Integrin beta; Belongs to the integrin beta chain family. | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | 0.670 |
ITGB1 | TNS4 | ENSCAFP00000005722 | ENSCAFP00000023638 | Integrin beta; Belongs to the integrin beta chain family. | Tensin 4. | 0.919 |
MET | HGF | ENSCAFP00000041478 | ENSCAFP00000009539 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | Hepatocyte growth factor alpha chain; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization (By similarity); Belongs to the peptidase S1 family. Plasminogen subfamily. | 0.998 |
MET | ITGB1 | ENSCAFP00000041478 | ENSCAFP00000005722 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | Integrin beta; Belongs to the integrin beta chain family. | 0.670 |
MET | TNS4 | ENSCAFP00000041478 | ENSCAFP00000023638 | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] | Tensin 4. | 0.543 |
PPP1R14D | TNS4 | ENSCAFP00000013777 | ENSCAFP00000023638 | Protein phosphatase 1 regulatory inhibitor subunit 14D. | Tensin 4. | 0.546 |
RITA1 | TNS1 | ENSCAFP00000039415 | ENSCAFP00000061457 | RBPJ interacting and tubulin associated 1. | Tensin 1. | 0.480 |
RITA1 | TNS4 | ENSCAFP00000039415 | ENSCAFP00000023638 | RBPJ interacting and tubulin associated 1. | Tensin 4. | 0.509 |
SBSPON | TNS4 | ENSCAFP00000035786 | ENSCAFP00000023638 | Somatomedin B and thrombospondin type 1 domain containing. | Tensin 4. | 0.515 |
TNS1 | EXOC6B | ENSCAFP00000061457 | ENSCAFP00000013203 | Tensin 1. | Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. | 0.536 |
TNS1 | RITA1 | ENSCAFP00000061457 | ENSCAFP00000039415 | Tensin 1. | RBPJ interacting and tubulin associated 1. | 0.480 |
TNS1 | TNS4 | ENSCAFP00000061457 | ENSCAFP00000023638 | Tensin 1. | Tensin 4. | 0.515 |