IGFBP4 protein (Canis lupus familiaris) - STRING interaction network

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Score

IGFBP4

Insulin like growth factor binding protein 4. (258 aa)

Predicted Functional Partners:

IGF1

0.989

IGF2

0.887

IGFBP3

0.793

LOC102152531

0.726

LOC100687249

0.726

PAPPA

0.672

IGFBP2

0.551

PAPPA2

0.549

IGFBP6

0.529

FAM20C

0.499

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FAM20C	IGFBP3	ENSCAFP00000016449	ENSCAFP00000018107	FAM20C golgi associated secretory pathway kinase.	Insulin like growth factor binding protein 3.	0.580
FAM20C	IGFBP4	ENSCAFP00000016449	ENSCAFP00000023677	FAM20C golgi associated secretory pathway kinase.	Insulin like growth factor binding protein 4.	0.499
IGF1	IGF2	ENSCAFP00000058639	ENSCAFP00000063478	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	Insulin like growth factor 2.	0.955
IGF1	IGFBP2	ENSCAFP00000058639	ENSCAFP00000021381	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	Insulin like growth factor binding protein 2.	0.984
IGF1	IGFBP3	ENSCAFP00000058639	ENSCAFP00000018107	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	Insulin like growth factor binding protein 3.	0.999
IGF1	IGFBP4	ENSCAFP00000058639	ENSCAFP00000023677	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	Insulin like growth factor binding protein 4.	0.989
IGF1	IGFBP6	ENSCAFP00000058639	ENSCAFP00000052653	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	Insulin like growth factor binding protein 6.	0.977
IGF1	PAPPA	ENSCAFP00000058639	ENSCAFP00000005199	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	Pappalysin 1.	0.665
IGF1	PAPPA2	ENSCAFP00000058639	ENSCAFP00000020996	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	Pappalysin 2.	0.566
IGF2	IGF1	ENSCAFP00000063478	ENSCAFP00000058639	Insulin like growth factor 2.	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	0.955
IGF2	IGFBP2	ENSCAFP00000063478	ENSCAFP00000021381	Insulin like growth factor 2.	Insulin like growth factor binding protein 2.	0.936
IGF2	IGFBP3	ENSCAFP00000063478	ENSCAFP00000018107	Insulin like growth factor 2.	Insulin like growth factor binding protein 3.	0.966
IGF2	IGFBP4	ENSCAFP00000063478	ENSCAFP00000023677	Insulin like growth factor 2.	Insulin like growth factor binding protein 4.	0.887
IGF2	IGFBP6	ENSCAFP00000063478	ENSCAFP00000052653	Insulin like growth factor 2.	Insulin like growth factor binding protein 6.	0.985
IGF2	PAPPA	ENSCAFP00000063478	ENSCAFP00000005199	Insulin like growth factor 2.	Pappalysin 1.	0.668
IGF2	PAPPA2	ENSCAFP00000063478	ENSCAFP00000020996	Insulin like growth factor 2.	Pappalysin 2.	0.582
IGFBP2	IGF1	ENSCAFP00000021381	ENSCAFP00000058639	Insulin like growth factor binding protein 2.	Insulin-like growth factor I; The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]- 2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. Ca(2+)-dependent exo [...]	0.984
IGFBP2	IGF2	ENSCAFP00000021381	ENSCAFP00000063478	Insulin like growth factor binding protein 2.	Insulin like growth factor 2.	0.936
IGFBP2	IGFBP3	ENSCAFP00000021381	ENSCAFP00000018107	Insulin like growth factor binding protein 2.	Insulin like growth factor binding protein 3.	0.445
IGFBP2	IGFBP4	ENSCAFP00000021381	ENSCAFP00000023677	Insulin like growth factor binding protein 2.	Insulin like growth factor binding protein 4.	0.551