STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DAGLADiacylglycerol lipase alpha. (901 aa)    
Predicted Functional Partners:
DAGLB
Diacylglycerol lipase beta.
     
0.904
PLAAT5
Phospholipase A and acyltransferase 5.
      
 0.846
NAPEPLD
N-acyl phosphatidylethanolamine phospholipase D.
      
 0.843
ABHD6
Abhydrolase domain containing 6.
      
 0.830
FAAH
Fatty acid amide hydrolase.
      
 0.796
CNR1
Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...]
      
 0.737
ABHD12
Abhydrolase domain containing 12.
      
 0.726
SERINC1
Serine incorporator 1.
      
 0.707
RUSC2
RUN and SH3 domain containing 2.
      
 0.693
AP4B1
AP complex subunit beta; Belongs to the adaptor complexes large subunit family.
      
 0.686
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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