STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LBRLamin B receptor. (618 aa)    
Predicted Functional Partners:
CYP51A1
Cytochrome P450 family 51 subfamily A member 1; Belongs to the cytochrome P450 family.
   
 0.988
EMD
Emerin.
   
 
 0.957
MSMO1
Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.
   
 0.957
DHCR24
24-dehydrocholesterol reductase.
 
 
 0.938
KPNB1
Karyopherin subunit beta 1.
    
 0.916
LMNB1
Lamin B1; Belongs to the intermediate filament family.
   
 
 0.908
SC5D
Sterol-C5-desaturase; Belongs to the sterol desaturase family.
   
 0.887
SUN2
Sad1 and UNC84 domain containing 2.
   
  
 0.861
MECP2
Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).
    
 0.861
ERG28
Ergosterol biosynthesis 28 homolog.
   
 
 0.859
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.