NWD2 protein (Canis lupus familiaris) - STRING interaction network

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Predicted Interactions

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[Homology]

Score

NWD2

NACHT and WD repeat domain containing 2. (1742 aa)

Predicted Functional Partners:

WDR93

0.854

APBB1IP

0.802

SPSB4

0.796

PEX11A

0.757

DLGAP1

0.713

CWH43

0.708

FAM184B

0.699

ARHGAP12

0.681

RAPGEF2

0.676

PXYLP1

0.574

Your Current Organism:

Canis lupus familiaris

NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APBB1IP	ARHGAP12	ENSCAFP00000006427	ENSCAFP00000006019	Amyloid beta precursor protein binding family B member 1 interacting protein.	Rho GTPase activating protein 12.	0.630
APBB1IP	CWH43	ENSCAFP00000006427	ENSCAFP00000002934	Amyloid beta precursor protein binding family B member 1 interacting protein.	Cell wall biogenesis 43 C-terminal homolog.	0.623
APBB1IP	DLGAP1	ENSCAFP00000006427	ENSCAFP00000046340	Amyloid beta precursor protein binding family B member 1 interacting protein.	DLG associated protein 1.	0.605
APBB1IP	FAM184B	ENSCAFP00000006427	ENSCAFP00000022218	Amyloid beta precursor protein binding family B member 1 interacting protein.	Family with sequence similarity 184 member B.	0.598
APBB1IP	NWD2	ENSCAFP00000006427	ENSCAFP00000023962	Amyloid beta precursor protein binding family B member 1 interacting protein.	NACHT and WD repeat domain containing 2.	0.802
APBB1IP	PEX11A	ENSCAFP00000006427	ENSCAFP00000041462	Amyloid beta precursor protein binding family B member 1 interacting protein.	Peroxisomal biogenesis factor 11 alpha.	0.662
APBB1IP	RAPGEF2	ENSCAFP00000006427	ENSCAFP00000066461	Amyloid beta precursor protein binding family B member 1 interacting protein.	Rap guanine nucleotide exchange factor 2; Functions as a guanine nucleotide exchange factor (GEF), which activates Rap and Ras family of small GTPases by exchanging bound GDP for free GTP in a cAMP-dependent manner. Serves as a link between cell surface receptors and Rap/Ras GTPases in intracellular signaling cascades. Acts also as an effector for Rap1 by direct association with Rap1-GTP thereby leading to the amplification of Rap1-mediated signaling. Shows weak activity on HRAS. It is controversial whether RAPGEF2 binds cAMP and cGMP or not. Its binding to ligand-activated beta-1 adre [...]	0.596
APBB1IP	SPSB4	ENSCAFP00000006427	ENSCAFP00000011346	Amyloid beta precursor protein binding family B member 1 interacting protein.	SplA/ryanodine receptor domain and SOCS box containing 4.	0.655
APBB1IP	WDR93	ENSCAFP00000006427	ENSCAFP00000017670	Amyloid beta precursor protein binding family B member 1 interacting protein.	WD repeat domain 93.	0.788
ARHGAP12	APBB1IP	ENSCAFP00000006019	ENSCAFP00000006427	Rho GTPase activating protein 12.	Amyloid beta precursor protein binding family B member 1 interacting protein.	0.630
ARHGAP12	CWH43	ENSCAFP00000006019	ENSCAFP00000002934	Rho GTPase activating protein 12.	Cell wall biogenesis 43 C-terminal homolog.	0.517
ARHGAP12	DLGAP1	ENSCAFP00000006019	ENSCAFP00000046340	Rho GTPase activating protein 12.	DLG associated protein 1.	0.478
ARHGAP12	FAM184B	ENSCAFP00000006019	ENSCAFP00000022218	Rho GTPase activating protein 12.	Family with sequence similarity 184 member B.	0.464
ARHGAP12	NWD2	ENSCAFP00000006019	ENSCAFP00000023962	Rho GTPase activating protein 12.	NACHT and WD repeat domain containing 2.	0.681
ARHGAP12	PEX11A	ENSCAFP00000006019	ENSCAFP00000041462	Rho GTPase activating protein 12.	Peroxisomal biogenesis factor 11 alpha.	0.564
ARHGAP12	RAPGEF2	ENSCAFP00000006019	ENSCAFP00000066461	Rho GTPase activating protein 12.	Rap guanine nucleotide exchange factor 2; Functions as a guanine nucleotide exchange factor (GEF), which activates Rap and Ras family of small GTPases by exchanging bound GDP for free GTP in a cAMP-dependent manner. Serves as a link between cell surface receptors and Rap/Ras GTPases in intracellular signaling cascades. Acts also as an effector for Rap1 by direct association with Rap1-GTP thereby leading to the amplification of Rap1-mediated signaling. Shows weak activity on HRAS. It is controversial whether RAPGEF2 binds cAMP and cGMP or not. Its binding to ligand-activated beta-1 adre [...]	0.496
ARHGAP12	SPSB4	ENSCAFP00000006019	ENSCAFP00000011346	Rho GTPase activating protein 12.	SplA/ryanodine receptor domain and SOCS box containing 4.	0.560
ARHGAP12	WDR93	ENSCAFP00000006019	ENSCAFP00000017670	Rho GTPase activating protein 12.	WD repeat domain 93.	0.670
CWH43	APBB1IP	ENSCAFP00000002934	ENSCAFP00000006427	Cell wall biogenesis 43 C-terminal homolog.	Amyloid beta precursor protein binding family B member 1 interacting protein.	0.623
CWH43	ARHGAP12	ENSCAFP00000002934	ENSCAFP00000006019	Cell wall biogenesis 43 C-terminal homolog.	Rho GTPase activating protein 12.	0.517