STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DEGS1Delta 4-desaturase, sphingolipid 1. (316 aa)    
Predicted Functional Partners:
CERS2
Ceramide synthase 2.
   
 0.958
SGMS2
Sphingomyelin synthase 2.
   
 
 0.957
CERS6
Ceramide synthase 6.
   
 0.956
CERS5
Ceramide synthase 5.
   
 0.956
CERS4
Ceramide synthase 4.
   
 0.956
SGMS1
Sphingomyelin synthase 1.
   
 
 0.952
SMPD2
Sphingomyelin phosphodiesterase 2.
   
 
 0.951
CERS3
Ceramide synthase 3.
   
 0.951
SMPD4
Sphingomyelin phosphodiesterase 4.
   
 
 0.950
SMPD3
Sphingomyelin phosphodiesterase 3.
     
 0.949
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.