STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAB24RAB24, member RAS oncogene family. (203 aa)    
Predicted Functional Partners:
RABGEF1
RAB guanine nucleotide exchange factor 1.
   
 
 0.924
SEL1L
SEL1L adaptor subunit of ERAD E3 ubiquitin ligase.
      
 0.875
RABGGTA
Rab geranylgeranyltransferase subunit alpha.
   
 0.861
APPL2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
   
 
 0.851
APPL1
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1.
    
 
 0.851
GPRIN1
G protein regulated inducer of neurite outgrowth 1.
   
 
 0.806
KCNJ10
Potassium voltage-gated channel subfamily J member 10.
      
 0.790
GRM1
Glutamate metabotropic receptor 1.
      
 0.789
ITPR1
Inositol 1,4,5-trisphosphate receptor type 1.
   
  
 0.788
SPTBN2
Spectrin beta chain; Belongs to the spectrin family.
   
  
 0.742
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.