STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAD2L1HORMA domain-containing protein. (267 aa)    
Predicted Functional Partners:
CDC20
Cell division cycle 20.
   
 0.990
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
 0.987
BUB1B
BUB1 mitotic checkpoint serine/threonine kinase B.
   
 0.986
MAD1L1
Mitotic arrest deficient 1 like 1.
   
 0.984
BUB3
BUB3 mitotic checkpoint protein.
   
 0.972
MAD2L2
Mitotic arrest deficient 2 like 2.
   
 0.934
NEK2
NIMA related kinase 2.
   
 0.931
CDC27
Cell division cycle 27.
   
 0.925
ANAPC4
Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family.
   
 0.914
ANAPC10
Anaphase-promoting complex subunit 10; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle.
   
 0.912
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.