node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CRIM1 | FAM81A | ENSCAFP00000008820 | ENSCAFP00000024500 | Cysteine rich transmembrane BMP regulator 1. | Family with sequence similarity 81 member A. | 0.492 |
CRIM1 | FMO3 | ENSCAFP00000008820 | ENSCAFP00000022069 | Cysteine rich transmembrane BMP regulator 1. | Dimethylaniline monooxygenase [N-oxide-forming] 3; Essential hepatic enzyme that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including drugs as well as dietary compounds. Plays an important role in the metabolism of trimethylamine (TMA), via the production of trimethylamine N-oxide (TMAO) metabolite. TMA is generated by the action of gut microbiota using dietary precursors such as choline, choline containing compounds, betaine or L-carnitine. By regulating TMAO concentration, FMO3 directly impacts both platelet responsiveness and rate of thr [...] | 0.434 |
CRIM1 | MN1 | ENSCAFP00000008820 | ENSCAFP00000017388 | Cysteine rich transmembrane BMP regulator 1. | MN1 proto-oncogene, transcriptional regulator. | 0.451 |
CRIM1 | RECQL | ENSCAFP00000008820 | ENSCAFP00000059876 | Cysteine rich transmembrane BMP regulator 1. | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. | 0.456 |
DDAH1 | FAM81A | ENSCAFP00000040838 | ENSCAFP00000024500 | Dimethylarginine dimethylaminohydrolase 1. | Family with sequence similarity 81 member A. | 0.517 |
DDAH1 | PTPN20 | ENSCAFP00000040838 | ENSCAFP00000064586 | Dimethylarginine dimethylaminohydrolase 1. | Protein tyrosine phosphatase non-receptor type 20. | 0.515 |
FAM81A | CRIM1 | ENSCAFP00000024500 | ENSCAFP00000008820 | Family with sequence similarity 81 member A. | Cysteine rich transmembrane BMP regulator 1. | 0.492 |
FAM81A | DDAH1 | ENSCAFP00000024500 | ENSCAFP00000040838 | Family with sequence similarity 81 member A. | Dimethylarginine dimethylaminohydrolase 1. | 0.517 |
FAM81A | FMO3 | ENSCAFP00000024500 | ENSCAFP00000022069 | Family with sequence similarity 81 member A. | Dimethylaniline monooxygenase [N-oxide-forming] 3; Essential hepatic enzyme that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including drugs as well as dietary compounds. Plays an important role in the metabolism of trimethylamine (TMA), via the production of trimethylamine N-oxide (TMAO) metabolite. TMA is generated by the action of gut microbiota using dietary precursors such as choline, choline containing compounds, betaine or L-carnitine. By regulating TMAO concentration, FMO3 directly impacts both platelet responsiveness and rate of thr [...] | 0.503 |
FAM81A | LMBR1L | ENSCAFP00000024500 | ENSCAFP00000012757 | Family with sequence similarity 81 member A. | Limb development membrane protein 1 like; Belongs to the LIMR family. | 0.670 |
FAM81A | MN1 | ENSCAFP00000024500 | ENSCAFP00000017388 | Family with sequence similarity 81 member A. | MN1 proto-oncogene, transcriptional regulator. | 0.564 |
FAM81A | PTPN20 | ENSCAFP00000024500 | ENSCAFP00000064586 | Family with sequence similarity 81 member A. | Protein tyrosine phosphatase non-receptor type 20. | 0.692 |
FAM81A | RECQL | ENSCAFP00000024500 | ENSCAFP00000059876 | Family with sequence similarity 81 member A. | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. | 0.568 |
FAM81A | SLC6A9 | ENSCAFP00000024500 | ENSCAFP00000059161 | Family with sequence similarity 81 member A. | Solute carrier family 6 member 9. | 0.499 |
FAM81A | TMED6 | ENSCAFP00000024500 | ENSCAFP00000030065 | Family with sequence similarity 81 member A. | GOLD domain-containing protein. | 0.518 |
FAM81A | TOR2A | ENSCAFP00000024500 | ENSCAFP00000047238 | Family with sequence similarity 81 member A. | Torsin. | 0.603 |
FMO3 | CRIM1 | ENSCAFP00000022069 | ENSCAFP00000008820 | Dimethylaniline monooxygenase [N-oxide-forming] 3; Essential hepatic enzyme that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including drugs as well as dietary compounds. Plays an important role in the metabolism of trimethylamine (TMA), via the production of trimethylamine N-oxide (TMAO) metabolite. TMA is generated by the action of gut microbiota using dietary precursors such as choline, choline containing compounds, betaine or L-carnitine. By regulating TMAO concentration, FMO3 directly impacts both platelet responsiveness and rate of thr [...] | Cysteine rich transmembrane BMP regulator 1. | 0.434 |
FMO3 | FAM81A | ENSCAFP00000022069 | ENSCAFP00000024500 | Dimethylaniline monooxygenase [N-oxide-forming] 3; Essential hepatic enzyme that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including drugs as well as dietary compounds. Plays an important role in the metabolism of trimethylamine (TMA), via the production of trimethylamine N-oxide (TMAO) metabolite. TMA is generated by the action of gut microbiota using dietary precursors such as choline, choline containing compounds, betaine or L-carnitine. By regulating TMAO concentration, FMO3 directly impacts both platelet responsiveness and rate of thr [...] | Family with sequence similarity 81 member A. | 0.503 |
FMO3 | MN1 | ENSCAFP00000022069 | ENSCAFP00000017388 | Dimethylaniline monooxygenase [N-oxide-forming] 3; Essential hepatic enzyme that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including drugs as well as dietary compounds. Plays an important role in the metabolism of trimethylamine (TMA), via the production of trimethylamine N-oxide (TMAO) metabolite. TMA is generated by the action of gut microbiota using dietary precursors such as choline, choline containing compounds, betaine or L-carnitine. By regulating TMAO concentration, FMO3 directly impacts both platelet responsiveness and rate of thr [...] | MN1 proto-oncogene, transcriptional regulator. | 0.459 |
FMO3 | RECQL | ENSCAFP00000022069 | ENSCAFP00000059876 | Dimethylaniline monooxygenase [N-oxide-forming] 3; Essential hepatic enzyme that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including drugs as well as dietary compounds. Plays an important role in the metabolism of trimethylamine (TMA), via the production of trimethylamine N-oxide (TMAO) metabolite. TMA is generated by the action of gut microbiota using dietary precursors such as choline, choline containing compounds, betaine or L-carnitine. By regulating TMAO concentration, FMO3 directly impacts both platelet responsiveness and rate of thr [...] | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. | 0.471 |