STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RNF40E3 ubiquitin protein ligase; Belongs to the BRE1 family. (1001 aa)    
Predicted Functional Partners:
RNF20
E3 ubiquitin protein ligase; Belongs to the BRE1 family.
  
0.997
UBE2B
Ubiquitin conjugating enzyme E2 B; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.856
UBE2A
Ubiquitin conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.856
LOC488290
Histone H2B; Belongs to the histone H2B family.
    
 0.856
WAC
WW domain-containing protein.
   
 0.807
H2BC1
Histone H2B; Belongs to the histone H2B family.
    
 0.772
LEO1
LEO1 homolog, Paf1/RNA polymerase II complex component.
   
 0.764
CDC73
Cell division cycle 73.
   
 0.762
PAF1
PAF1 homolog, Paf1/RNA polymerase II complex component.
   
 0.748
ENSCAFP00000056145
UBIQUITIN_CONJUGAT_2 domain-containing protein.
   
 
 0.725
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.