STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZNF646Zinc finger protein 646. (1811 aa)    
Predicted Functional Partners:
PALD1
Phosphatase domain containing paladin 1.
   
  
 0.790
ADAMTS14
ADAM metallopeptidase with thrombospondin type 1 motif 14.
   
  
 0.679
RNF40
E3 ubiquitin protein ligase; Belongs to the BRE1 family.
   
 
 0.606
ZDHHC24
Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family.
   
 
 0.593
ADGRV1
Adhesion G protein-coupled receptor V1; Belongs to the G-protein coupled receptor 2 family.
    
 
 0.563
SETD1A
SET domain containing 1A, histone lysine methyltransferase.
   
 
 0.563
CCDC93
Coiled-coil domain containing 93.
      
 0.563
ASB8
Ankyrin repeat and SOCS box containing 8.
   
 
 0.553
STX4
Syntaxin 4; Belongs to the syntaxin family.
    
 
 0.537
PARP2
Poly [ADP-ribose] polymerase.
    
 
 0.526
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.