STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VKORC1Vitamin K epoxide reductase complex subunit 1. (163 aa)    
Predicted Functional Partners:
GGCX
Gamma-glutamyl carboxylase.
   
 
 0.979
NQO1
NAD(P)H quinone dehydrogenase 1.
   
 
 0.927
VKORC1L1
VKc domain-containing protein.
  
 
 
0.903
XPR1
Uncharacterized protein.
      
 0.713
TRPT1
tRNA phosphotransferase 1.
   
  
 0.687
PRSS53
Serine protease 53; Belongs to the peptidase S1 family.
 
  
 
 0.563
THYN1
Thymocyte nuclear protein 1.
   
  
 0.560
DCLRE1A
DNA cross-link repair 1A.
   
  
 0.519
PLCD3
Phosphoinositide phospholipase C.
   
  
 0.517
HCCS
Cytochrome c heme lyase; Links covalently the heme group to the apoprotein of cytochrome c.
      
 0.504
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.