STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CHD3Chromodomain helicase DNA binding protein 3. (1977 aa)    
Predicted Functional Partners:
GATAD2A
GATA zinc finger domain containing 2A.
   
 0.947
GATAD2B
GATA zinc finger domain containing 2B.
   
 0.925
RBBP7
RB binding protein 7, chromatin remodeling factor.
   
 0.894
HDAC1
Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
   
 0.893
MTA1
Metastasis associated 1.
   
 0.891
MTA2
Metastasis associated 1 family member 2.
   
 0.890
HDAC2
Histone deacetylase 2.
   
 0.874
CHD4
Chromodomain helicase DNA binding protein 4.
  
0.872
MTA3
Metastasis associated 1 family member 3.
   
 0.868
ENSCAFP00000058271
WD_REPEATS_REGION domain-containing protein.
   
 0.866
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.