STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM117AFamily with sequence similarity 117 member A. (453 aa)    
Predicted Functional Partners:
SLC35B1
Solute carrier family 35 member B1.
 
    
 0.767
UBE2Z
Ubiquitin conjugating enzyme E2 Z.
      
 0.560
SNF8
Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family.
   
  
 0.552
PHOSPHO1
Phosphoethanolamine/phosphocholine phosphatase.
      
 0.511
CALCOCO2
Calcium binding and coiled-coil domain 2.
   
  
 0.465
ITIH1
Inter-alpha-trypsin inhibitor heavy chain 1.
   
  
 0.414
ABI3
ABI family member 3.
   
  
 0.410
DLX3
Distal-less homeobox 3.
   
  
 0.408
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.