STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HERC1HECT and RLD domain containing E3 ubiquitin protein ligase family member 1. (4860 aa)    
Predicted Functional Partners:
GEM
GTP-binding protein; Belongs to the small GTPase superfamily. RGK family.
    
 
 0.795
BIRC6
Baculoviral IAP repeat containing 6.
   
 
 0.752
MDN1
Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family.
   
 
 0.739
LOC488297
Histone H2A; Belongs to the histone H2A family.
    
 
 0.710
MYCBP2
MYC binding protein 2.
   
 
0.707
KIAA1109
KIAA1109.
   
   0.612
HERC2
HECT and RLD domain containing E3 ubiquitin protein ligase 2.
   
 
0.590
NEURL4
Uncharacterized protein.
    
 
 0.571
RSAD2
Radical S-adenosyl methionine domain containing 2.
      
 0.568
TOB2
Transducer of ERBB2, 2.
      
 0.561
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.