STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
XYLT2Xylosyltransferase 2; Catalyzes the first step in the biosynthesis of chondroitin sulfate, heparan sulfate and dermatan sulfate proteoglycans, such as DCN (By similarity). Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein (By similarity). Belongs to the glycosyltransferase 14 family. XylT subfamily. (865 aa)    
Predicted Functional Partners:
B4GALT7
Beta-1,4-galactosyltransferase 7.
   
 
 0.984
XYLT1
Xylosyltransferase 1; Catalyzes the first step in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans, such as DCN. Transfers D- xylose from UDP-D-xylose to specific serine residues of the core protein. Required for normal maturation of chondrocytes during bone development, normal onset of ossification and normal embryonic and postnatal skeleton development, especially of the long bones.
  
  
0.905
EXTL3
Exostosin like glycosyltransferase 3; Belongs to the glycosyltransferase 47 family.
   
  
 0.885
SLC35B2
Solute carrier family 35 member B2.
   
  
 0.874
EXTL2
Exostosin like glycosyltransferase 2.
      
 0.860
HS2ST1
Uncharacterized protein.
    
 
 0.829
SDC1
Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.
   
 0.719
B3GAT3
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family.
   
  
 0.694
CASD1
CAS1 domain containing 1.
      
 0.679
CSGALNACT1
Hexosyltransferase.
      
 0.611
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.