STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DAND5DAN domain BMP antagonist family member 5. (190 aa)    
Predicted Functional Partners:
SWT1
SWT1 RNA endoribonuclease homolog.
      
 0.757
TRMT1L
tRNA methyltransferase 1 like; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family.
   
  
 0.737
RNF2
Ring finger protein 2.
      
 0.711
BMP4
TGF_BETA_2 domain-containing protein.
    
 
 0.679
IVNS1ABP
Influenza virus NS1A binding protein.
      
 0.604
FMN2
Formin 2.
    
 
 0.585
CCR5
C-C chemokine receptor type 5; Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation (By similarity).
      
 0.567
OPN3
Opsin 3; Belongs to the G-protein coupled receptor 1 family.
      
 0.566
GCDH
Glutaryl-CoA dehydrogenase.
      
 0.517
GADD45GIP1
GADD45G interacting protein 1.
      
 0.515
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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