STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SYCE2Synaptonemal complex central element protein 2. (167 aa)    
Predicted Functional Partners:
SYCE1
Synaptonemal complex central element protein 1.
   
  
 0.985
TEX12
Testis expressed 12.
    
 
 0.942
SYCE3
Synaptonemal complex central element protein 3.
    
 
 0.926
SYCE1L
Synaptonemal complex central element protein 1 like.
      
 0.872
SYCP1
Synaptonemal complex protein 1.
    
 
 0.866
MSH5
DNA_MISMATCH_REPAIR_2 domain-containing protein.
   
  
 0.807
ATAT1
Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dyn [...]
      
 0.777
RAE1
SPO11 initiator of meiotic double stranded breaks.
   
  
 0.761
LOC102152531
Cor1 domain-containing protein.
      
 0.731
LOC100687249
Cor1 domain-containing protein.
      
 0.731
Your Current Organism:
Canis lupus familiaris
NCBI taxonomy Id: 9615
Other names: C. lupus familiaris, Canis canis, Canis domesticus, Canis familiaris, beagle dog, beagle dogs, dog, dogs
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.